--- title: "Cortisone and anti-inflammatory drugs before/shortly after PMMA - PhalloBoards - Phalloboards" description: "Does anyone know why Dr C gives a cortisone shot before the PMMA procedure? I am guessing the advantage would be less swelling which lessens the risk of early..." url: "https://j4.phalloboards.info/general-forum/general-phalloplasty-discussion-archive/5704184-cortisone-and-anti-inflammatory-drugs-before-shortly-after-pmma.html" date: "2026-08-06T16:57:11+00:00" language: "en-GB" --- PhalloBoards - An Online Community to Discuss Penile Girth Enhancement General Forum Doctors Forum Username Password Remember me - [ Forgot your password? ](https://j4.phalloboards.info/component/users/reset.html?Itemid=101) - [ Forgot your username? ](https://j4.phalloboards.info/component/users/remind.html?Itemid=101) - [ Create an account ](https://j4.phalloboards.info/register.html) # TOPIC: Cortisone and anti-inflammatory drugs before/shortly after PMMA ## Re: Cortisone and anti-inflammatory drugs before/shortly after PMMA 14 years 5 months ago [\#1272196922](#1272196922) - **[Miracle8x7](https://j4.phalloboards.info/general-forum/user/1724055-miracle8x7.html "View Miracle8x7's Profile")** - [![Miracle8x7's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/1724055-miracle8x7.html "View Miracle8x7's Profile") - [ Offline](https://j4.phalloboards.info/general-forum/user/1724055-miracle8x7.html) - Moderator - ![Moderator](https://j4.phalloboards.info/media/kunena/ranks/rankmod.gif) - Posts: 1328 - Thanks: 1 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=1724055) Androgen is correct regarding the use of NSAID's. It is best to allow one's body to attempt to heal naturally and not interfere with the process. Maintaining a healthy diet will surely aid the body's ability to heal as will quality sleep. Those prone to keloid scarring will not necessarily achieve better gains though. Collagen deposition caused by microsphere implantation is determined by one's unique reaction and the health and age of the individual. Luck of the draw to an extent. Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtcGhhbGxvcGxhc3R5LWRpc2N1c3Npb24tYXJjaGl2ZS81NzA0MTg0LWNvcnRpc29uZS1hbmQtYW50aS1pbmZsYW1tYXRvcnktZHJ1Z3MtYmVmb3JlLXNob3J0bHktYWZ0ZXItcG1tYS5odG1sP21hcmtkb3duPTE=) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. ## Cortisone and anti-inflammatory drugs before/shortly after PMMA 14 years 5 months ago [\#1272191855](#1272191855) - **[gst](https://j4.phalloboards.info/general-forum/user/1829648-gst.html "View gst's Profile")** - [![gst's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/1829648-gst.html "View gst's Profile") Topic Author - [ Offline](https://j4.phalloboards.info/general-forum/user/1829648-gst.html) - General - ![General](https://j4.phalloboards.info/media/kunena/ranks/rank1.gif) - Posts: 23 - Thanks: 0 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=1829648) Does anyone know why Dr C gives a cortisone shot before the PMMA procedure? I am guessing the advantage would be less swelling which lessens the risk of early PMMA displacement causing distortion of the initially achieved contours. Or am I imagining this? Less swelling also means less discomfort or pain. But from reading this board pain does not seem to be an issue even in those who had the procedure done by doctors other than Dr C. The obvious risk would be that of infection (especially those with old grafts). Would a potential disadvantage be less Girth gain? The anti-inflammatory effect would attract less immune cells to the site of "injury". I understand the immune cells then orchestrate fibroblast migration from around day 3 onwards and it is these cells that lay down collagen. The effect of cortisone should have worn off by then but by dampening the initial burst of inflammatory activity wouldn't it change the composition of the inflammatory "soup" surrounding the PMMA in the first week? Does this lessen scar-tissue type collagen formation and improve the feel of the penis? Has Dr C given this a thought and concluded that the benefits outweigh the risks or disadvantages? Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtcGhhbGxvcGxhc3R5LWRpc2N1c3Npb24tYXJjaGl2ZS81NzA0MTg0LWNvcnRpc29uZS1hbmQtYW50aS1pbmZsYW1tYXRvcnktZHJ1Z3MtYmVmb3JlLXNob3J0bHktYWZ0ZXItcG1tYS5odG1sP21hcmtkb3duPTE=) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. ## Re: Cortisone and anti-inflammatory drugs before/shortly after PMMA 14 years 5 months ago [\#1272192697](#1272192697) - **[gst](https://j4.phalloboards.info/general-forum/user/1829648-gst.html "View gst's Profile")** - [![gst's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/1829648-gst.html "View gst's Profile") Topic Author - [ Offline](https://j4.phalloboards.info/general-forum/user/1829648-gst.html) - General - ![General](https://j4.phalloboards.info/media/kunena/ranks/rank1.gif) - Posts: 23 - Thanks: 0 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=1829648) @Socalt I think your logic may be flawed. People with autoimmune conditions do not naturally have stronger immunity. They just have an abnormal immune response to their own body tissues. That said any meds you take might well affect the result as it may also alter your normal immune/healing response. You may be at higher risk of infection after the procedure if you remain on your normal medication. Dr C may well advise you against the procedure or he may ask you to stay on your meds and give you strong antibiotics, who knows? Maybe you can write to him about this and share his answers with us? My guess would be people who tend to get big unsightly scars may well gain the most Girth from PMMA. Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtcGhhbGxvcGxhc3R5LWRpc2N1c3Npb24tYXJjaGl2ZS81NzA0MTg0LWNvcnRpc29uZS1hbmQtYW50aS1pbmZsYW1tYXRvcnktZHJ1Z3MtYmVmb3JlLXNob3J0bHktYWZ0ZXItcG1tYS5odG1sP21hcmtkb3duPTE=) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. ## Re: Cortisone and anti-inflammatory drugs before/shortly after PMMA 14 years 5 months ago [\#1272196793](#1272196793) - **[Androgen](https://j4.phalloboards.info/general-forum/user/1853690-androgen.html "View Androgen's Profile")** - [![Androgen's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/1853690-androgen.html "View Androgen's Profile") - [ Offline](https://j4.phalloboards.info/general-forum/user/1853690-androgen.html) - General - ![General](https://j4.phalloboards.info/media/kunena/ranks/rank1.gif) - Posts: 44 - Thanks: 0 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=1853690) Hmm I'm curious about this as well. Woudn't an anti-inflammatory be counter productive immediately following a PMMA injection? I understand not wanting to endure pain/swelling but it's not something that happens for no reason. It's actually a good response from our body. If I'm not mistaken NSAID's will inhibit either COX 1 and COX 2 enzymes or one specifically.. Inhibiting these in a post injection situation can inhibit platelet aggregation. Which would be the opposite of what we want in terms of recovery correct? Someone correct me if I'm wrong but this is my understanding. Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtcGhhbGxvcGxhc3R5LWRpc2N1c3Npb24tYXJjaGl2ZS81NzA0MTg0LWNvcnRpc29uZS1hbmQtYW50aS1pbmZsYW1tYXRvcnktZHJ1Z3MtYmVmb3JlLXNob3J0bHktYWZ0ZXItcG1tYS5odG1sP21hcmtkb3duPTE=) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. 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