--- title: "Question about biofilm - PhalloBoards - Phalloboards" description: "Apologies if this has been asked before, but I could not find this specific point addressed in other conversations. Is biofilm formation possible at any point..." url: "https://j4.phalloboards.info/general-forum/general-discussion/10156677-question-about-biofilm.html" date: "2026-08-06T20:53:17+00:00" language: "en-GB" --- PhalloBoards - An Online Community to Discuss Penile Girth Enhancement General Forum Doctors Forum Username Password Remember me - [ Forgot your password? ](https://j4.phalloboards.info/component/users/reset.html?Itemid=101) - [ Forgot your username? ](https://j4.phalloboards.info/component/users/remind.html?Itemid=101) - [ Create an account ](https://j4.phalloboards.info/register.html) # TOPIC: Question about biofilm ## Question about biofilm 1 year 1 month ago [\#1308721892](#1308721892) - **[NardDog](https://j4.phalloboards.info/general-forum/user/6768183-narddog.html "View NardDog's Profile")** - [![NardDog's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/6768183-narddog.html "View NardDog's Profile") Topic Author - [ Offline](https://j4.phalloboards.info/general-forum/user/6768183-narddog.html) - Pending Email Verification - ![Pending Email Verification](https://j4.phalloboards.info/media/kunena/ranks/rank2.gif) - Posts: 16 - Thanks: 1 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=6768183) Apologies if this has been asked before, but I could not find this specific point addressed in other conversations. Is biofilm formation possible at any point after the procedure or is it limited to the short time period after the injection of PMMA? For example, if I were to get a full body infection unrelated to the PMMA injection would I then potentially get biofilm formation in my penis? And would this then require surgical intervention to remove the PMMA? Is it a just a risk that has to be accepted- that any point following the procedure I could suddenly have biofilm formation. Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtZGlzY3Vzc2lvbi8xMDE1NjY3Ny1xdWVzdGlvbi1hYm91dC1iaW9maWxtLmh0bWw/bWFya2Rvd249MQ==) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. ## Re: Question about biofilm 1 year 1 month ago [\#1308721922](#1308721922) - **[Dr\_Sullivan](https://j4.phalloboards.info/general-forum/user/6769476-dr-sullivan.html "View Dr_Sullivan's Profile")** - [![Dr_Sullivan's Avatar](https://j4.phalloboards.info/media/kunena/core/svg/person.svg)](https://j4.phalloboards.info/general-forum/user/6769476-dr-sullivan.html "View Dr_Sullivan's Profile") - [ Offline](https://j4.phalloboards.info/general-forum/user/6769476-dr-sullivan.html) - Pending Email Verification - ![Pending Email Verification](https://j4.phalloboards.info/media/kunena/ranks/rank2.gif) - Posts: 151 - Thanks: 78 - [ ](https://j4.phalloboards.info/pms.html?task=new&recip=6769476) Biofilm‐associated infection is almost exclusively an early-post-injection issue and even then it is a very minimal risk. • In the first 2-8 weeks the PMMA microspheres are still being integrated in the body. During this window bacteria introduced at the time of injection—or in the rare case of early cellulitis—can adhere and organize into a biofilm. • By ~3-6 months a dense collagen capsule surrounds each 30-40 µm microsphere, physically separating it from the bloodstream and greatly reducing the possibility of bacterial adhesion. As for late biofilm formation, any foreign material can, in theory, be colonized during a bout of bacteremia (e.g., severe pneumonia or sepsis). However, after millions of PMMA injections over two decades, only isolated case reports exist. Why? The combination of small particle size, smooth surface, and collagen encapsulation makes secondary seeding extraordinarily unlikely. • Once you pass the three-month mark the probability of a new biofilm forming is infinitesimally small. • No special lifelong precautions or prophylactic antibiotics are recommended. Bottom line: biofilm formation is primarily an early-integration concern. After the PMMA is fully collagen-encased, late infection is theoretically possible but practically negligible. Hope that helps. Dr. S The following user(s) said Thank You: [NardDog](https://j4.phalloboards.info/general-forum/user/6768183-narddog.html "View NardDog's Profile"), [FlaccidAcid](https://j4.phalloboards.info/general-forum/user/6772791-flaccidacid.html "View FlaccidAcid's Profile"), [rodandstaff2025](https://j4.phalloboards.info/general-forum/user/6775149-rodandstaff2025.html "View rodandstaff2025's Profile"), [zaddy](https://j4.phalloboards.info/general-forum/user/6777468-zaddy.html "View zaddy's Profile") Please [Log in](https://j4.phalloboards.info/login.html?return=aHR0cHM6Ly9qNC5waGFsbG9ib2FyZHMuaW5mby9nZW5lcmFsLWZvcnVtL2dlbmVyYWwtZGlzY3Vzc2lvbi8xMDE1NjY3Ny1xdWVzdGlvbi1hYm91dC1iaW9maWxtLmh0bWw/bWFya2Rvd249MQ==) or [Create an account](https://j4.phalloboards.info/register.html) to join the conversation. 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